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Carcinogenesis Inside of a life span carcinogenicity study completed in B6C3F1 mice, methylphenidate induced an increase in hepatocellular adenomas, and in males only, a rise in hepatoblastomas in a day-to-day dose of approximately 60 mg/kg/day. This dose is somewhere around two occasions the MRHD of sixty mg/day specified to youngsters on mg/m2 fo